Program

5th MARCH 2020 (Thursday) 

Due to unpredictable problems that affected the travelling options of our main speaker the
Biomedica/ One Lambda PRE-EWIC Symposium has to be cancelled. 
There will be no symposium on the 5th of March between 13.00 – 16.00.
The EWIC program will start with the Opening at 17.00 on Thursday, 5th of March.

A short lecture on current NGS developments is beeing scheduled  for Friday, 6th of March
at 15:50 as a 15 minutes symposium.

17:00-18:00 OPENING
(Chairs: Aniko Szilvasi, Antonij Slavcev, Gottfried Fischer)
Welcome speech
Sandor Nagy (HU)
The Birth of HLA
Frans Claas (NL)
Role of donor Specific antibodies in Renal Transplantation
Laszlo Wagner (HU)

18:00-20:00 Welcome Reception in the Apicius Restaurant (Aquincum Hotel)
Starting with performance of Bartók Folk Dance Group

6th MARCH 2020 (Friday)

08:45-10:15 STEM CELL TRANSPLANTATION
(Chairs: Frantisek Mrazek and Gottfried Fischer)

Histocompatibility in Allogeneic Stem Cell Transpalntation from unrelated donors,  
What to Search and wath to Match for
Joannis Mytilineos (DE)
Result of  haplotransplantation with TCR alpha/beta depletion in Budapest
Gergely Krivan (HU)
Engraftment monitoring after hemotopoietic stem cell transplantation
Marco Adreani (IT)
Challenges for the HLA laboratory- Haploidentical Transplantation
Gottfried Fischer (A)

10:15-10:30  Symposium
Solving Biological Mysteries with NGS
Sebastian Ziemann (GenDx)

10:30-11:00 Coffee Break

11:00-12:10 SOLID ORGAN TRANSPLANTATION
(Chairs: Renata Zunec, Aniko Szilvasi)
The Eurotransplant Acceptable Mismatch Program in the evolving field of histocompatibility
Marissa van der Linden van Oevelen (NL)
Organ Donation and Transplantation Program Coordination in Hungary and in the Eurotransplant Area
Sandor Mihaly (HU)
Flow cytometry crossmatch and HLA incompatible transplantation-a single center experience
Antonij Slavcev (CZ)

12:10-12:30 Break

12:30-14:00 Lunch Symposium
 Symposium
PAIRED WORKFLOW SOLUTION FOR BEST IN CLASS HLA MATCHING

Introduction
John Norton (CareDx)
Real time PCR in donor search for HLA identical and haploidentical hematopoetic cell transplants
Milena Vrana (CZ)
Hibrid Capture-A Novel NGS approach for High Resolution HLA Typing and Beyond
Bushra Nabil al Hadra (BG)


 Symposium
GENOME-WIDE APPROACHES FOR IDENTIFICATION OF DISEASE-ASSOCATED GENE VARIANTS:
BASE CONCEPTS AND EXAMPLES
Frantisek Mrazek (CZ) 
Vera Siffnerova (Omixon)
Libor Kolesar (Omixon)


14:00-15:20 ABSTRACT PRESENTATIONS I.
(Chairs: Irina Pavlova and Marco Adreani)
Presentation time is max. 10 min./abstract

Donor Specific Cell Free DNA levels in Recipients’ Plasma after Lung Transplantation
Ingrid Fae (A)
Different antibody response to implanted cryopreserved native versus decellularized heart valves
Sabine Wenda (A)
Incidence of HLA antibody specificities not included in eurotranspalnt allocation system in pretransplant sera of kidney graft recipients
Renata Zunec (HR)
HLA-typing and virtual crossmatches in european kidney exchange programmes
Peter Biro (H)
Development of the local registry of HSC donors in Russia during 2017-2019
Irina Pavlova (RU)
Selection of suitable unrelated hematopoietic stem cell donor
Sara Nazarova (CZ)
Availability of stem cell donors including haploidentical family members – recent single centre experience
Milena Vrana (CZ)
Family study confirmed rare HLA-A*02:778 allele in the patient indicated for allogeneic HSCT
Frantisek Mrazek (CZ)

15:20-15:50 Coffee Break

15:50-16:05       Symposium
FASTPLEX-THE MOST ADVANCED NGS WORKFLOW FOR HLA TYPING
Curtis Lind (Thermo Fischer Scientific)

16:05-17:35 CLINICAL TRANSPLANTATION
(Chairs: Andreas Zuckermann, Sabine Wenda and Jean-Luc Taupin)
Heart Transplantation in Austria
Andreas Zuckermann (A)
Heart Transplantation and Mechanical Circulatory Support in Hungary-
Results of the last 10 years
Istvan Hartyanszky (HU)
DSA after Lungtransplantation. Facts and doubts
Gabriella Murakozi (A)
HLA antibody assessment and risk stratification in organ transplantation
Jean-Luc Taupin (FR)

17:35-18:00 POSTER WALK
19:00-22:00 Conference Dinner  in Rozmaring Restaurant , sponsored by 


7th MARCH 2020 (Saturday)

08:45-10:30 POPULATION GENETICS & DISEASE
(Chairs: Martin Petrek and Zorana Grubic)
Kidney Paired Donation in UK
Frank JMF Dor (UK)
HLA-Disease Association Testing in the Era of Next-Generation Sequencing
Eszter Lazar-Molnar (US)
Are HLA rare alleles truly rare, or just waiting to be reported?
The importance of HLA population data submission
Zorana Grubic (HR)
TBA
Blanka Vidan-Jeras (SL)
HLA genotype shapes driven leukemogenesis
Milena Ivanova (BG)

10:30-11:00 Coffee Break

11:00-12:30 ABSTRACT PRESENTATIONS II.
(Chairs: Katarzyna Bogunia-Kubik and Milena Vrana)

Functional activating KIR–Cognate HLA pairs in unrelated hematopoietic stem cell transplantation in malignancy
Jacek Nowak (PL)
Association of rank and rankl gene polymorphism with survival and calcium levels in multiple myeloma
Marta Dratwa (PL)
Frequency of ambiguities in NGS HLA typing of 11 LOCI
Boban Dobrevski (MK)
Haplotyping Hungarian pediatric all HLA-Class II genes using NGS
Livia Lazar (HU)
NGS-based HLA-typing for patients with blood disorders and hematopoietic stem cell donors
Ekaterina Khamaganova (RU)
Concordance of methods of quantitative analysis of chimerism after allogenic stem cell transplantation
Maria Loginova (RU)
Disease relapse and loss of mismatched HLA haplotype in haploidentical stem cell transplantation
Marija Maskalan (HR)
Association of HLA variants with sarcoidosis in Korean population- pilot study
Katerina Sikorova (CZ)
Do you know what it takes to CE mark a HLA typing product?
Gergely Tolgyesi (HU)

12:30-13:30 Lunch 

13:30-15:00 EFI AFFAIRS 
Wroclaw HLA external proficiency testing- lesson learnded from 20 years of activity
Katarzyna Bogunia-Kubik (PL)
Results of external proficiency testing for cell chimerism analysis in 2019
Bara Cizkova (CZ)
Different Antibody Response to implanted cryopreserved native versus decellularized heart valves
Ingrid Fae (A)
CET 2019 analysis 
Gottfried Fischer (A)
EFI Accreditaion Program in Region 8
Milena Ivanova (BG)
Update on EFI region 5a
Blanka Vidan-Jeras (SL)
Results of external proficiency testing „DETECTION OF HLA ALLELES ASSOCIATED WITH DISEASES“  in 2019
Milena Vrana (CZ)

15:00-15:10 Closure